Daniel C. Alexander

Details

Position: Professor of Imaging Science
Department: Department of Computer Science
Institution: University College London
Address: Department of Computer Science, University College London, Gower Street, London WC1E 6BT
Phone: 020 7679 2419
Home page: http://www.cs.ucl.ac.uk/staff/D.Alexander/
E-mail: D.Alexander at cs.ucl.ac.uk

Publications

Please note that the following is an automatically retrieved selection of papers relating to diffusion MRI, and is not a complete list of publications by this author.

Palombo M, Ianus A, Guerreri M, Nunes D, Alexander DC, Shemesh N, Zhang H (2020). Corrigendum to "SANDI: A compartment-based model for non-invasive apparent soma and neurite imaging by diffusion MRI" [Neuroimage 215 (2020), 116835]. Neuroimage 226:117612. [PubMed]
Tanno R, Worrall DE, Kaden E, Ghosh A, Grussu F, Bizzi A, Sotiropoulos SN, Criminisi A, Alexander DC (2021). Uncertainty modelling in deep learning for safer neuroimage enhancement: Demonstration in diffusion MRI. Neuroimage 225:117366. [PubMed]
Hill I, Palombo M, Santin M, Branzoli F, Philippe AC, Wassermann D, Aigrot MS, Stankoff B, Baron-Van Evercooren A, Felfli M, Langui D, Zhang H, Lehericy S, Petiet A, Alexander DC, Ciccarelli O, Drobnjak I (2021). Machine learning based white matter models with permeability: An experimental study in cuprizone treated in-vivo mouse model of axonal demyelination. Neuroimage 224:117425. [PubMed]
Ning L, Bonet-Carne E, Grussu F, Sepehrband F, Kaden E, Veraart J, Blumberg SB, Khoo CS, Palombo M, Kokkinos I, Alexander DC, Coll-Font J, Scherrer B, Warfield SK, Karayumak SC, Rathi Y, Koppers S, Weninger L, Ebert J, Merhof D, Moyer D, Pietsch M, Christiaens D, Gomes Teixeira RA, Tournier JD, Schilling KG, Huo Y, Nath V, Hansen C, Blaber J, Landman BA, Zhylka A, Pluim JPW, Parker G, Rudrapatna U, Evans J, Charron C, Jones DK, Tax CMW (2020). Cross-scanner and cross-protocol multi-shell diffusion MRI data harmonization: Algorithms and results. Neuroimage 221:117128. [PubMed]
Callaghan R, Alexander DC, Palombo M, Zhang H (2020). ConFiG: Contextual Fibre Growth to generate realistic axonal packing for diffusion MRI simulation. Neuroimage 220:117107. [PubMed]
Pascuzzo R, Oxtoby NP, Young AL, Blevins J, Castelli G, Garbarino S, Cohen ML, Schonberger LB, Gambetti P, Appleby BS, Alexander DC, Bizzi A (2020). Prion propagation estimated from brain diffusion MRI is subtype dependent in sporadic Creutzfeldt-Jakob disease. Acta Neuropathol 140(2):169-181. [PubMed]
Roberts TA, Hyare H, Agliardi G, Hipwell B, d'Esposito A, Ianus A, Breen-Norris JO, Ramasawmy R, Taylor V, Atkinson D, Punwani S, Lythgoe MF, Siow B, Brandner S, Rees J, Panagiotaki E, Alexander DC, Walker-Samuel S (2020). Noninvasive diffusion magnetic resonance imaging of brain tumour cell size for the early detection of therapeutic response. Sci Rep 10(1):9223. [PubMed]
Kaden E, Gyori NG, Rudrapatna SU, Barskaya IY, Dragonu I, Does MD, Jones DK, Clark CA, Alexander DC (2020). Microscopic susceptibility anisotropy imaging. Magn Reson Med 84(5):2739-2753. [PubMed]
Gabel MC, Broad RJ, Young AL, Abrahams S, Bastin ME, Menke RAL, Al-Chalabi A, Goldstein LH, Tsermentseli S, Alexander DC, Turner MR, Leigh PN, Cercignani M (2020). Evolution of white matter damage in amyotrophic lateral sclerosis. Ann Clin Transl Neurol 7(5):722-732. [PubMed]
Grussu F, Battiston M, Veraart J, Schneider T, Cohen-Adad J, Shepherd TM, Alexander DC, Fieremans E, Novikov DS, Gandini Wheeler-Kingshott CAM (2020). Multi-parametric quantitative in vivo spinal cord MRI with unified signal readout and image denoising. Neuroimage 217:116884. [PubMed]
Palombo M, Ianus A, Guerreri M, Nunes D, Alexander DC, Shemesh N, Zhang H (2020). SANDI: A compartment-based model for non-invasive apparent soma and neurite imaging by diffusion MRI. Neuroimage 215:116835. [PubMed]
Breen-Norris JO, Siow B, Walsh C, Hipwell B, Hill I, Roberts T, Hall MG, Lythgoe MF, Ianus A, Alexander DC, Walker-Samuel S (2020). Measuring diffusion exchange across the cell membrane with DEXSY (Diffusion Exchange Spectroscopy). Magn Reson Med 84(3):1543-1551. [PubMed]
Ianus A, Santiago I, Galzerano A, Montesinos P, Loucao N, Sanchez-Gonzalez J, Alexander DC, Matos C, Shemesh N (2020). Higher-order diffusion MRI characterization of mesorectal lymph nodes in rectal cancer. Magn Reson Med 84(1):348-364. [PubMed]
Collorone S, Cawley N, Grussu F, Prados F, Tona F, Calvi A, Kanber B, Schneider T, Kipp L, Zhang H, Alexander DC, Thompson AJ, Toosy A, Wheeler-Kingshott CAG, Ciccarelli O (2020). Reduced neurite density in the brain and cervical spinal cord in relapsing-remitting multiple sclerosis: A NODDI study. Mult Scler 26(13):1647-1657. [PubMed]
Christiaens D, Slator PJ, Cordero-Grande L, Price AN, Deprez M, Alexander DC, Rutherford M, Hajnal JV, Hutter J (2019). In Utero Diffusion MRI: Challenges, Advances, and Applications. Top Magn Reson Imaging 28(5):255-264. [PubMed]
Bagnato F, Franco G, Li H, Kaden E, Ye F, Fan R, Chen A, Alexander DC, Smith SA, Dortch R, Xu J (2019). Probing axons using multi-compartmental diffusion in multiple sclerosis. Ann Clin Transl Neurol 6(9):1595-1605. [PubMed]
Pecheva D, Tournier JD, Pietsch M, Christiaens D, Batalle D, Alexander DC, Hajnal JV, Edwards AD, Zhang H, Counsell SJ (2019). Fixel-based analysis of the preterm brain: Disentangling bundle-specific white matter microstructural and macrostructural changes in relation to clinical risk factors. Neuroimage Clin 23:101820. [PubMed]
Slator PJ, Hutter J, Palombo M, Jackson LH, Ho A, Panagiotaki E, Chappell LC, Rutherford MA, Hajnal JV, Alexander DC (2019). Combined diffusion-relaxometry MRI to identify dysfunction in the human placenta. Magn Reson Med 82(1):95-106. [PubMed]
Marinescu RV, Eshaghi A, Lorenzi M, Young AL, Oxtoby NP, Garbarino S, Crutch SJ, Alexander DC (2019). DIVE: A spatiotemporal progression model of brain pathology in neurodegenerative disorders. Neuroimage 192:166-177. [PubMed]
Kelly CJ, Christiaens D, Batalle D, Makropoulos A, Cordero-Grande L, Steinweg JK, O'Muircheartaigh J, Khan H, Lee G, Victor S, Alexander DC, Zhang H, Simpson J, Hajnal JV, Edwards AD, Rutherford MA, Counsell SJ (2019). Abnormal Microstructural Development of the Cerebral Cortex in Neonates With Congenital Heart Disease Is Associated With Impaired Cerebral Oxygen Delivery. J Am Heart Assoc 8(5):e009893. [PubMed]
Bailey C, Bourne RM, Siow B, Johnston EW, Brizmohun Appayya M, Pye H, Heavey S, Mertzanidou T, Whitaker H, Freeman A, Patel D, Shaw GL, Sridhar A, Hawkes DJ, Punwani S, Alexander DC, Panagiotaki E (2019). VERDICT MRI validation in fresh and fixed prostate specimens using patient-specific moulds for histological and MR alignment. NMR Biomed 32(5):e4073. [PubMed]
Tax CM, Grussu F, Kaden E, Ning L, Rudrapatna U, John Evans C, St-Jean S, Leemans A, Koppers S, Merhof D, Ghosh A, Tanno R, Alexander DC, Zappala S, Charron C, Kusmia S, Linden DE, Jones DK, Veraart J (2019). Cross-scanner and cross-protocol diffusion MRI data harmonisation: A benchmark database and evaluation of algorithms. Neuroimage 195:285-299. [PubMed]
Devine W, Giganti F, Johnston EW, Sidhu HS, Panagiotaki E, Punwani S, Alexander DC, Atkinson D (2019). Simplified Luminal Water Imaging for the Detection of Prostate Cancer From Multiecho T2 MR Images. J Magn Reson Imaging 50(3):910-917. [PubMed]
Palombo M, Alexander DC, Zhang H (2019). A generative model of realistic brain cells with application to numerical simulation of the diffusion-weighted MR signal. Neuroimage 188:391-402. [PubMed]
Bonet-Carne E, Johnston E, Daducci A, Jacobs JG, Freeman A, Atkinson D, Hawkes DJ, Punwani S, Alexander DC, Panagiotaki E (2019). VERDICT-AMICO: Ultrafast fitting algorithm for non-invasive prostate microstructure characterization. NMR Biomed 32(1):e4019. [PubMed]
Broad RJ, Gabel MC, Dowell NG, Schwartzman DJ, Seth AK, Zhang H, Alexander DC, Cercignani M, Leigh PN (2019). Neurite orientation and dispersion density imaging (NODDI) detects cortical and corticospinal tract degeneration in ALS. J Neurol Neurosurg Psychiatry 90(4):404-411. [PubMed]
Wen J, Zhang H, Alexander DC, Durrleman S, Routier A, Rinaldi D, Houot M, Couratier P, Hannequin D, Pasquier F, Zhang J, Colliot O, Le Ber I, Bertrand A (2019). Neurite density is reduced in the presymptomatic phase of C9orf72 disease. J Neurol Neurosurg Psychiatry 90(4):387-394. [PubMed]
Hutter J, Slator PJ, Jackson L, Gomes ADS, Ho A, Story L, O'Muircheartaigh J, Teixeira RPAG, Chappell LC, Alexander DC, Rutherford MA, Hajnal JV (2019). Multi-modal functional MRI to explore placental function over gestation. Magn Reson Med 81(2):1191-1204. [PubMed]
Grussu F, Ianus A, Tur C, Prados F, Schneider T, Kaden E, Ourselin S, Drobnjak I, Zhang H, Alexander DC, Gandini Wheeler-Kingshott CAM (2019). Relevance of time-dependence for clinically viable diffusion imaging of the spinal cord. Magn Reson Med 81(2):1247-1264. [PubMed]
Ianus A, Jespersen SN, Serradas Duarte T, Alexander DC, Drobnjak I, Shemesh N (2018). Accurate estimation of microscopic diffusion anisotropy and its time dependence in the mouse brain. Neuroimage 183:934-949. [PubMed]
Batalle D, O'Muircheartaigh J, Makropoulos A, Kelly CJ, Dimitrova R, Hughes EJ, Hajnal JV, Zhang H, Alexander DC, Edwards AD, Counsell SJ (2019). Different patterns of cortical maturation before and after 38 weeks gestational age demonstrated by diffusion MRI in vivo. Neuroimage 185:764-775. [PubMed]
Jones DK, Alexander DC, Bowtell R, Cercignani M, Dell'Acqua F, McHugh DJ, Miller KL, Palombo M, Parker GJM, Rudrapatna US, Tax CMW (2018). Microstructural imaging of the human brain with a 'super-scanner': 10 key advantages of ultra-strong gradients for diffusion MRI. Neuroimage 182:8-38. [PubMed]
Parker TD, Slattery CF, Zhang J, Nicholas JM, Paterson RW, Foulkes AJM, Malone IB, Thomas DL, Modat M, Cash DM, Crutch SJ, Alexander DC, Ourselin S, Fox NC, Zhang H, Schott JM (2018). Cortical microstructure in young onset Alzheimer's disease using neurite orientation dispersion and density imaging. Hum Brain Mapp 39(7):3005-3017. [PubMed]
Bailey C, Collins DJ, Tunariu N, Orton MR, Morgan VA, Feiweier T, Hawkes DJ, Leach MO, Alexander DC, Panagiotaki E (2018). Microstructure Characterization of Bone Metastases from Prostate Cancer with Diffusion MRI: Preliminary Findings. Front Oncol 8:26. [PubMed]
Ganepola T, Nagy Z, Ghosh A, Papadopoulo T, Alexander DC, Sereno MI (2018). Using diffusion MRI to discriminate areas of cortical grey matter. Neuroimage 182:456-468. [PubMed]
Slator PJ, Hutter J, McCabe L, Gomes ADS, Price AN, Panagiotaki E, Rutherford MA, Hajnal JV, Alexander DC (2018). Placenta microstructure and microcirculation imaging with diffusion MRI. Magn Reson Med 80(2):756-766. [PubMed]
West KL, Kelm ND, Carson RP, Alexander DC, Gochberg DF, Does MD (2018). Experimental studies of g-ratio MRI in ex vivo mouse brain. Neuroimage 167:366-371. [PubMed]
Alexander DC, Dyrby TB, Nilsson M, Zhang H (2019). Imaging brain microstructure with diffusion MRI: practicality and applications. NMR Biomed 32(4):e3841. [PubMed]
Alfaro-Almagro F, Jenkinson M, Bangerter NK, Andersson JLR, Griffanti L, Douaud G, Sotiropoulos SN, Jbabdi S, Hernandez-Fernandez M, Vallee E, Vidaurre D, Webster M, McCarthy P, Rorden C, Daducci A, Alexander DC, Zhang H, Dragonu I, Matthews PM, Miller KL, Smith SM (2018). Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank. Neuroimage 166:400-424. [PubMed]
Grussu F, Schneider T, Tur C, Yates RL, Tachrount M, Ianus A, Yiannakas MC, Newcombe J, Zhang H, Alexander DC, DeLuca GC, Gandini Wheeler-Kingshott CAM (2017). Neurite dispersion: a new marker of multiple sclerosis spinal cord pathology?. Ann Clin Transl Neurol 4(9):663-679. [PubMed]
Bastiani M, Cottaar M, Dikranian K, Ghosh A, Zhang H, Alexander DC, Behrens TE, Jbabdi S, Sotiropoulos SN (2017). Improved tractography using asymmetric fibre orientation distributions. Neuroimage 158:205-218. [PubMed]
Ferizi U, Scherrer B, Schneider T, Alipoor M, Eufracio O, Fick RHJ, Deriche R, Nilsson M, Loya-Olivas AK, Rivera M, Poot DHJ, Ramirez-Manzanares A, Marroquin JL, Rokem A, Potter C, Dougherty RF, Sakaie K, Wheeler-Kingshott C, Warfield SK, Witzel T, Wald LL, Raya JG, Alexander DC (2017). Diffusion MRI microstructure models with in vivo human brain Connectome data: results from a multi-group comparison. NMR Biomed 30(9). [PubMed]
Slattery CF, Zhang J, Paterson RW, Foulkes AJM, Carton A, Macpherson K, Mancini L, Thomas DL, Modat M, Toussaint N, Cash DM, Thornton JS, Henley SMD, Crutch SJ, Alexander DC, Ourselin S, Fox NC, Zhang H, Schott JM (2017). ApoE influences regional white-matter axonal density loss in Alzheimer's disease. Neurobiol Aging 57:8-17. [PubMed]
Pecheva D, Yushkevich P, Batalle D, Hughes E, Aljabar P, Wurie J, Hajnal JV, Edwards AD, Alexander DC, Counsell SJ, Zhang H (2017). A tract-specific approach to assessing white matter in preterm infants. Neuroimage 157:675-694. [PubMed]
Alexander DC, Zikic D, Ghosh A, Tanno R, Wottschel V, Zhang J, Kaden E, Dyrby TB, Sotiropoulos SN, Zhang H, Criminisi A (2017). Image quality transfer and applications in diffusion MRI. Neuroimage 152:283-298. [PubMed]
Nedjati-Gilani GL, Schneider T, Hall MG, Cawley N, Hill I, Ciccarelli O, Drobnjak I, Wheeler-Kingshott CAMG, Alexander DC (2017). Machine learning based compartment models with permeability for white matter microstructure imaging. Neuroimage 150:119-135. [PubMed]
Batalle D, Hughes EJ, Zhang H, Tournier JD, Tusor N, Aljabar P, Wali L, Alexander DC, Hajnal JV, Nosarti C, Edwards AD, Counsell SJ (2017). Early development of structural networks and the impact of prematurity on brain connectivity. Neuroimage 149:379-392. [PubMed]
Bailey C, Siow B, Panagiotaki E, Hipwell JH, Mertzanidou T, Owen J, Gazinska P, Pinder SE, Alexander DC, Hawkes DJ (2017). Microstructural models for diffusion MRI in breast cancer and surrounding stroma: an ex vivo study. NMR Biomed 30(2). [PubMed]
Grussu F, Schneider T, Yates RL, Zhang H, Wheeler-Kingshott CAMG, DeLuca GC, Alexander DC (2016). A framework for optimal whole-sample histological quantification of neurite orientation dispersion in the human spinal cord. J Neurosci Methods 273:20-32. [PubMed]
Ianus A, Shemesh N, Alexander DC, Drobnjak I (2017). Double oscillating diffusion encoding and sensitivity to microscopic anisotropy. Magn Reson Med 78(2):550-564. [PubMed]
Sepehrband F, Alexander DC, Clark KA, Kurniawan ND, Yang Z, Reutens DC (2016). Parametric Probability Distribution Functions for Axon Diameters of Corpus Callosum. Front Neuroanat 10:59. [PubMed]
Kaden E, Kelm ND, Carson RP, Does MD, Alexander DC (2016). Multi-compartment microscopic diffusion imaging. Neuroimage 139:346-359. [PubMed]
Ianus A, Drobnjak I, Alexander DC (2016). Model-based estimation of microscopic anisotropy using diffusion MRI: a simulation study. NMR Biomed 29(5):672-85. [PubMed]
Tariq M, Schneider T, Alexander DC, Gandini Wheeler-Kingshott CA, Zhang H (2016). Bingham-NODDI: Mapping anisotropic orientation dispersion of neurites using diffusion MRI. Neuroimage 133:207-223. [PubMed]
Sepehrband F, Alexander DC, Kurniawan ND, Reutens DC, Yang Z (2016). Towards higher sensitivity and stability of axon diameter estimation with diffusion-weighted MRI. NMR Biomed 29(3):293-308. [PubMed]
Colgan N, Siow B, O'Callaghan JM, Harrison IF, Wells JA, Holmes HE, Ismail O, Richardson S, Alexander DC, Collins EC, Fisher EM, Johnson R, Schwarz AJ, Ahmed Z, O'Neill MJ, Murray TK, Zhang H, Lythgoe MF (2016). Application of neurite orientation dispersion and density imaging (NODDI) to a tau pathology model of Alzheimer's disease. Neuroimage 125:739-744. [PubMed]
Shemesh N, Jespersen SN, Alexander DC, Cohen Y, Drobnjak I, Dyrby TB, Finsterbusch J, Koch MA, Kuder T, Laun F, Lawrenz M, Lundell H, Mitra PP, Nilsson M, Ozarslan E, Topgaard D, Westin CF (2016). Conventions and nomenclature for double diffusion encoding NMR and MRI. Magn Reson Med 75(1):82-7. [PubMed]
Ianus A, Drobnjak I, Alexander DC (2015). Model-Based Estimation of Microscopic Anisotropy in Macroscopically Isotropic Substrates Using Diffusion MRI. Inf Process Med Imaging 24:699-710. [PubMed]
Ferizi U, Schneider T, Witzel T, Wald LL, Zhang H, Wheeler-Kingshott CA, Alexander DC (2015). White matter compartment models for in vivo diffusion MRI at 300mT/m. Neuroimage 118:468-83. [PubMed]
Clayden JD, Nagy Z, Weiskopf N, Alexander DC, Clark CA (2016). Microstructural parameter estimation in vivo using diffusion MRI and structured prior information. Magn Reson Med 75(4):1787-96. [PubMed]
Kaden E, Kruggel F, Alexander DC (2016). Quantitative mapping of the per-axon diffusion coefficients in brain white matter. Magn Reson Med 75(4):1752-63. [PubMed]
Drobnjak I, Zhang H, Ianus A, Kaden E, Alexander DC (2016). PGSE, OGSE, and sensitivity to axon diameter in diffusion MRI: Insight from a simulation study. Magn Reson Med 75(2):688-700. [PubMed]
Grussu F, Schneider T, Zhang H, Alexander DC, Wheeler-Kingshott CA (2015). Neurite orientation dispersion and density imaging of the healthy cervical spinal cord in vivo. Neuroimage 111:590-601. [PubMed]
Figini M, Alexander DC, Redaelli V, Fasano F, Grisoli M, Baselli G, Gambetti P, Tagliavini F, Bizzi A (2015). Mathematical models for the diffusion magnetic resonance signal abnormality in patients with prion diseases. Neuroimage Clin 7:142-54. [PubMed]
Daducci A, Canales-Rodriguez EJ, Zhang H, Dyrby TB, Alexander DC, Thiran JP (2015). Accelerated Microstructure Imaging via Convex Optimization (AMICO) from diffusion MRI data. Neuroimage 105:32-44. [PubMed]
Panagiotaki E, Chan RW, Dikaios N, Ahmed HU, O'Callaghan J, Freeman A, Atkinson D, Punwani S, Hawkes DJ, Alexander DC (2015). Microstructural characterization of normal and malignant human prostate tissue with vascular, extracellular, and restricted diffusion for cytometry in tumours magnetic resonance imaging. Invest Radiol 50(4):218-27. [PubMed]
Nedjati-Gilani GL, Schneider T, Hall MG, Wheeler-Kingshott CA, Alexander DC (2014). Machine learning based compartment models with permeability for white matter microstructure imaging. Med Image Comput Comput Assist Interv 17(Pt 3):257-64. [PubMed]
Tariq M, Schneider T, Alexander DC, Wheeler-Kingshott CA, Zhang H (2014). In vivo estimation of dispersion anisotropy of neurites using diffusion MRI. Med Image Comput Comput Assist Interv 17(Pt 3):241-8. [PubMed]
Alexander DC, Zikic D, Zhang J, Zhang H, Criminisi A (2014). Image quality transfer via random forest regression: applications in diffusion MRI. Med Image Comput Comput Assist Interv 17(Pt 3):225-32. [PubMed]
Lundell H, Alexander DC, Dyrby TB (2014). High angular resolution diffusion imaging with stimulated echoes: compensation and correction in experiment design and analysis. NMR Biomed 27(8):918-25. [PubMed]
Proverbio A, Siow BM, Lythgoe MF, Alexander DC, Gibson AP (2014). Multimodality characterization of microstructure by the combination of diffusion NMR and time-domain diffuse optical data. Phys Med Biol 59(11):2639-58. [PubMed]
Kunz N, Zhang H, Vasung L, O'Brien KR, Assaf Y, Lazeyras F, Alexander DC, Huppi PS (2014). Assessing white matter microstructure of the newborn with multi-shell diffusion MRI and biophysical compartment models. Neuroimage 96:288-99. [PubMed]
Norris FC, Siow BM, Cleary JO, Wells JA, De Castro SC, Ordidge RJ, Greene ND, Copp AJ, Scambler PJ, Alexander DC, Lythgoe MF (2015). Diffusion microscopic MRI of the mouse embryo: Protocol and practical implementation in the splotch mouse model. Magn Reson Med 73(2):731-9. [PubMed]
Ferizi U, Schneider T, Tariq M, Wheeler-Kingshott CA, Zhang H, Alexander DC (2013). The importance of being dispersed: A ranking of diffusion MRI models for fibre dispersion using in vivo human brain data. Med Image Comput Comput Assist Interv 16(Pt 1):74-81. [PubMed]
Panagiotaki E, Walker-Samuel S, Siow B, Johnson SP, Rajkumar V, Pedley RB, Lythgoe MF, Alexander DC (2014). Noninvasive quantification of solid tumor microstructure using VERDICT MRI. Cancer Res 74(7):1902-12. [PubMed]
Ferizi U, Schneider T, Panagiotaki E, Nedjati-Gilani G, Zhang H, Wheeler-Kingshott CA, Alexander DC (2014). A ranking of diffusion MRI compartment models with in vivo human brain data. Magn Reson Med 72(6):1785-92. [PubMed]
Winston GP, Micallef C, Symms MR, Alexander DC, Duncan JS, Zhang H (2014). Advanced diffusion imaging sequences could aid assessing patients with focal cortical dysplasia and epilepsy. Epilepsy Res 108(2):336-9. [PubMed]
Bourne RM, Panagiotaki E, Bongers A, Sved P, Watson G, Alexander DC (2014). Information theoretic ranking of four models of diffusion attenuation in fresh and fixed prostate tissue ex vivo. Magn Reson Med 72(5):1418-26. [PubMed]
Richardson S, Siow B, Panagiotaki E, Schneider T, Lythgoe MF, Alexander DC (2014). Viable and fixed white matter: diffusion magnetic resonance comparisons and contrasts at physiological temperature. Magn Reson Med 72(4):1151-61. [PubMed]
Assaf Y, Alexander DC, Jones DK, Bizzi A, Behrens TE, Clark CA, Cohen Y, Dyrby TB, Huppi PS, Knoesche TR, Lebihan D, Parker GJ, Poupon C, Anaby D, Anwander A, Bar L, Barazany D, Blumenfeld-Katzir T, De-Santis S, Duclap D, Figini M, Fischi E, Guevara P, Hubbard P, Hofstetter S, Jbabdi S, Kunz N, Lazeyras F, Lebois A, Liptrot MG, Lundell H, Mangin JF, Dominguez DM, Morozov D, Schreiber J, Seunarine K, Nava S, Poupon C, Riffert T, Sasson E, Schmitt B, Shemesh N, Sotiropoulos SN, Tavor I, Zhang HG, Zhou FL (2013). The CONNECT project: Combining macro- and micro-structure. Neuroimage 80:273-82. [PubMed]
Nagy Z, Alexander DC, Thomas DL, Weiskopf N, Sereno MI (2013). Using high angular resolution diffusion imaging data to discriminate cortical regions. PLoS One 8(5):e63842. [PubMed]
Ryan NS, Keihaninejad S, Shakespeare TJ, Lehmann M, Crutch SJ, Malone IB, Thornton JS, Mancini L, Hyare H, Yousry T, Ridgway GR, Zhang H, Modat M, Alexander DC, Rossor MN, Ourselin S, Fox NC (2013). Magnetic resonance imaging evidence for presymptomatic change in thalamus and caudate in familial Alzheimer's disease. Brain 136(Pt 5):1399-414. [PubMed]
Kaden E, Alexander DC (2013). Can T2-spectroscopy resolve submicrometer axon diameters?. Inf Process Med Imaging 23:607-18. [PubMed]
Rowe M, Zhang HG, Oxtoby N, Alexander DC (2013). Beyond crossing fibers: tractography exploiting sub-voxel fibre dispersion and neighbourhood structure. Inf Process Med Imaging 23:402-13. [PubMed]
Ianus A, Siow B, Drobnjak I, Zhang H, Alexander DC (2013). Gaussian phase distribution approximations for oscillating gradient spin echo diffusion MRI. J Magn Reson 227:25-34. [PubMed]
Campanella M, Molinari E, Baraldi P, Nocetti L, Porro CA, Alexander DC (2013). An algorithm to estimate anatomical connectivity between brain regions using diffusion MRI. Magn Reson Imaging 31(3):353-8. [PubMed]
Wheeler-Kingshott CA, Ciccarelli O, Schneider T, Alexander DC, Cercignani M (2012). A new approach to structural integrity assessment based on axial and radial diffusivities. Funct Neurol 27(2):85-90. [PubMed]
Dyrby TB, Sogaard LV, Hall MG, Ptito M, Alexander DC (2013). Contrast and stability of the axon diameter index from microstructure imaging with diffusion MRI. Magn Reson Med 70(3):711-21. [PubMed]
Richardson S, Siow B, Batchelor AM, Lythgoe MF, Alexander DC (2013). A viable isolated tissue system: a tool for detailed MR measurements and controlled perturbation in physiologically stable tissue. Magn Reson Med 69(6):1603-10. [PubMed]
Zhang H, Schneider T, Wheeler-Kingshott CA, Alexander DC (2012). NODDI: practical in vivo neurite orientation dispersion and density imaging of the human brain. Neuroimage 61(4):1000-16. [PubMed]
Siow B, Drobnjak I, Chatterjee A, Lythgoe MF, Alexander DC (2012). Estimation of pore size in a microstructure phantom using the optimised gradient waveform diffusion weighted NMR sequence. J Magn Reson 214(1):51-60. [PubMed]
Kleinnijenhuis M, Barth M, Alexander DC, van Cappellen van Walsum AM, Norris DG (2012). Structure Tensor Informed Fiber Tractography (STIFT) by combining gradient echo MRI and diffusion weighted imaging. Neuroimage 59(4):3941-54. [PubMed]
Panagiotaki E, Schneider T, Siow B, Hall MG, Lythgoe MF, Alexander DC (2012). Compartment models of the diffusion MR signal in brain white matter: a taxonomy and comparison. Neuroimage 59(3):2241-54. [PubMed]
Zhang H, Dyrby TB, Alexander DC (2011). Axon diameter mapping in crossing fibers with diffusion MRI. Med Image Comput Comput Assist Interv 14(Pt 2):82-9. [PubMed]
Drobnjak I, Alexander DC (2011). Optimising time-varying gradient orientation for microstructure sensitivity in diffusion-weighted MR. J Magn Reson 212(2):344-54. [PubMed]
Drobnjak I, Zhang H, Hall MG, Alexander DC (2011). The matrix formalism for generalised gradients with time-varying orientation in diffusion NMR. J Magn Reson 210(1):151-7. [PubMed]
Zhang H, Hubbard PL, Parker GJ, Alexander DC (2011). Axon diameter mapping in the presence of orientation dispersion with diffusion MRI. Neuroimage 56(3):1301-15. [PubMed]
Dyrby TB, Baare WF, Alexander DC, Jelsing J, Garde E, Sogaard LV (2011). An ex vivo imaging pipeline for producing high-quality and high-resolution diffusion-weighted imaging datasets. Hum Brain Mapp 32(4):544-63. [PubMed]
Panagiotaki E, Hall MG, Zhang H, Siow B, Lythgoe MF, Alexander DC (2010). High-fidelity meshes from tissue samples for diffusion MRI simulations. Med Image Comput Comput Assist Interv 13(Pt 2):404-11. [PubMed]
Zhang H, Alexander DC (2010). Axon diameter mapping in the presence of orientation dispersion with diffusion MRI. Med Image Comput Comput Assist Interv 13(Pt 1):640-7. [PubMed]
Schneider T, Wheeler-Kingshott CA, Alexander DC (2010). In-vivo estimates of axonal characteristics using optimized diffusion MRI protocols for single fibre orientation. Med Image Comput Comput Assist Interv 13(Pt 1):623-30. [PubMed]
Clarkson MJ, Malone IB, Modat M, Leung KK, Ryan N, Alexander DC, Fox NC, Ourselin S (2010). A framework for using diffusion weighted imaging to improve cortical parcellation. Med Image Comput Comput Assist Interv 13(Pt 1):534-41. [PubMed]
Sherbondy AJ, Rowe MC, Alexander DC (2010). MicroTrack: an algorithm for concurrent projectome and microstructure estimation. Med Image Comput Comput Assist Interv 13(Pt 1):183-90. [PubMed]
Yogarajah M, Focke NK, Bonelli SB, Thompson P, Vollmar C, McEvoy AW, Alexander DC, Symms MR, Koepp MJ, Duncan JS (2010). The structural plasticity of white matter networks following anterior temporal lobe resection. Brain 133(Pt 8):2348-64. [PubMed]
Alexander DC, Hubbard PL, Hall MG, Moore EA, Ptito M, Parker GJ, Dyrby TB (2010). Orientationally invariant indices of axon diameter and density from diffusion MRI. Neuroimage 52(4):1374-89. [PubMed]
Drobnjak I, Siow B, Alexander DC (2010). Optimizing gradient waveforms for microstructure sensitivity in diffusion-weighted MR. J Magn Reson 206(1):41-51. [PubMed]
Clayden JD, Nagy Z, Hall MG, Clark CA, Alexander DC (2009). Active imaging with dual spin-echo diffusion MRI. Inf Process Med Imaging 21:264-75. [PubMed]
Yogarajah M, Focke NK, Bonelli S, Cercignani M, Acheson J, Parker GJ, Alexander DC, McEvoy AW, Symms MR, Koepp MJ, Duncan JS (2009). Defining Meyer's loop-temporal lobe resections, visual field deficits and diffusion tensor tractography. Brain 132(Pt 6):1656-68. [PubMed]
Hall MG, Alexander DC (2009). Convergence and parameter choice for Monte-Carlo simulations of diffusion MRI. IEEE Trans Med Imaging 28(9):1354-64. [PubMed]
Haroon HA, Morris DM, Embleton KV, Alexander DC, Parker GJ (2009). Using the model-based residual bootstrap to quantify uncertainty in fiber orientations from Q-ball analysis. IEEE Trans Med Imaging 28(4):535-50. [PubMed]
Panagiotaki E, Fonteijn H, Siow B, Hall MG, Price A, Lythgoe MF, Alexander DC (2009). Two-compartment models of the diffusion MR signal in brain white matter. Med Image Comput Comput Assist Interv 12(Pt 1):329-36. [PubMed]
Alexander DC (2008). A general framework for experiment design in diffusion MRI and its application in measuring direct tissue-microstructure features. Magn Reson Med 60(2):439-48. [PubMed]
Draganski B, Kherif F, Kloppel S, Cook PA, Alexander DC, Parker GJ, Deichmann R, Ashburner J, Frackowiak RS (2008). Evidence for segregated and integrative connectivity patterns in the human Basal Ganglia. J Neurosci 28(28):7143-52. [PubMed]
Yogarajah M, Powell HW, Parker GJ, Alexander DC, Thompson PJ, Symms MR, Boulby P, Wheeler-Kingshott CA, Barker GJ, Koepp MJ, Duncan JS (2008). Tractography of the parahippocampal gyrus and material specific memory impairment in unilateral temporal lobe epilepsy. Neuroimage 40(4):1755-64. [PubMed]
Kloppel S, Draganski B, Golding CV, Chu C, Nagy Z, Cook PA, Hicks SL, Kennard C, Alexander DC, Parker GJ, Tabrizi SJ, Frackowiak RS (2008). White matter connections reflect changes in voluntary-guided saccades in pre-symptomatic Huntington's disease. Brain 131(Pt 1):196-204. [PubMed]
Nagy Z, Weiskopf N, Alexander DC, Deichmann R (2007). A method for improving the performance of gradient systems for diffusion-weighted MRI. Magn Reson Med 58(4):763-8. [PubMed]
Dyrby TB, Sogaard LV, Parker GJ, Alexander DC, Lind NM, Baare WF, Hay-Schmidt A, Eriksen N, Pakkenberg B, Paulson OB, Jelsing J (2007). Validation of in vitro probabilistic tractography. Neuroimage 37(4):1267-77. [PubMed]
Cook PA, Symms M, Boulby PA, Alexander DC (2007). Optimal acquisition orders of diffusion-weighted MRI measurements. J Magn Reson Imaging 25(5):1051-8. [PubMed]
Powell HW, Parker GJ, Alexander DC, Symms MR, Boulby PA, Wheeler-Kingshott CA, Barker GJ, Koepp MJ, Duncan JS (2007). Abnormalities of language networks in temporal lobe epilepsy. Neuroimage 36(1):209-21. [PubMed]
Alexander DC (2005). Maximum entropy spherical deconvolution for diffusion MRI. Inf Process Med Imaging 19:76-87. [PubMed]
Zhang H, Yushkevich PA, Alexander DC, Gee JC (2006). Deformable registration of diffusion tensor MR images with explicit orientation optimization. Med Image Anal 10(5):764-85. [PubMed]
Newton JM, Ward NS, Parker GJ, Deichmann R, Alexander DC, Friston KJ, Frackowiak RS (2006). Non-invasive mapping of corticofugal fibres from multiple motor areas--relevance to stroke recovery. Brain 129(Pt 7):1844-58. [PubMed]
Cook PA, Zhang H, Avants BB, Yushkevich P, Alexander DC, Gee JC, Ciccarelli O, Thompson AJ (2005). An automated approach to connectivity-based partitioning of brain structures. Med Image Comput Comput Assist Interv 8(Pt 1):164-71. [PubMed]
Powell HW, Parker GJ, Alexander DC, Symms MR, Boulby PA, Wheeler-Kingshott CA, Barker GJ, Noppeney U, Koepp MJ, Duncan JS (2006). Hemispheric asymmetries in language-related pathways: a combined functional MRI and tractography study. Neuroimage 32(1):388-99. [PubMed]
Alexander DC (2005). Multiple-fiber reconstruction algorithms for diffusion MRI. Ann N Y Acad Sci 1064:113-33. [PubMed]
Powell HW, Parker GJ, Alexander DC, Symms MR, Boulby PA, Wheeler-Kingshott CA, Barker GJ, Koepp MJ, Duncan JS (2005). MR tractography predicts visual field defects following temporal lobe resection. Neurology 65(4):596-9. [PubMed]
Parker GJ, Alexander DC (2005). Probabilistic anatomical connectivity derived from the microscopic persistent angular structure of cerebral tissue. Philos Trans R Soc Lond B Biol Sci 360(1457):893-902. [PubMed]
Alexander DC, Barker GJ (2005). Optimal imaging parameters for fiber-orientation estimation in diffusion MRI. Neuroimage 27(2):357-67. [PubMed]
Parker GJ, Luzzi S, Alexander DC, Wheeler-Kingshott CA, Ciccarelli O, Lambon Ralph MA (2005). Lateralization of ventral and dorsal auditory-language pathways in the human brain. Neuroimage 24(3):656-66. [PubMed]
Parker GJ, Alexander DC (2003). Probabilistic Monte Carlo based mapping of cerebral connections utilising whole-brain crossing fibre information. Inf Process Med Imaging 18:684-95. [PubMed]
Jansons KM, Alexander DC (2003). Persistent Angular Structure: new insights from diffusion MRI data. Dummy version. Inf Process Med Imaging 18:672-83. [PubMed]
Coulon O, Alexander DC, Arridge S (2004). Diffusion tensor magnetic resonance image regularization. Med Image Anal 8(1):47-67. [PubMed]
Jones DK, Griffin LD, Alexander DC, Catani M, Horsfield MA, Howard R, Williams SC (2002). Spatial normalization and averaging of diffusion tensor MRI data sets. Neuroimage 17(2):592-617. [PubMed]
Alexander DC, Barker GJ, Arridge SR (2002). Detection and modeling of non-Gaussian apparent diffusion coefficient profiles in human brain data. Magn Reson Med 48(2):331-40. [PubMed]
Alexander DC, Pierpaoli C, Basser PJ, Gee JC (2001). Spatial transformations of diffusion tensor magnetic resonance images. IEEE Trans Med Imaging 20(11):1131-9. [PubMed]